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Prof. Dr. Eckhard Schulz

Haus: B, Raum: 0412

+49 3683 688 5100

+49 3683 688 5499

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Prof. Dr. rer. nat. E. Schulz

Lehrgebiete

  • Mathematik
  • Physik

Forschung

Veröffentlichungen

Benndorf, K., Schulz, E. (2023),
Identifiability of equilibrium constants for receptors with two to five binding sites,
J. Gen. Physiol. (2023) 155 (12): e202313423; doi: 10.1085/jgp.202313423

Schmauder, R., Eick, T., Schulz, E., Sammler, G., Voigt, E., Mayer, G., Ginter, H., Ditze, G., Benndorf, K. (2023),
Fast functional mapping of ligand-gated ion channels,
Commun. Biol. (2023) 6: 1003 ; doi: 10.1038/s42003-023-05340-w

Benndorf, K., Eick, T., Sattler, C., Schmauder, R., and Schulz, E. (2022):
A strategy for determining the equilibrium constants for heteromeric ion channels in a complex model
J. Gen. Physiol. (2022) 154 (6): e202113041

Schirmeyer, J., Eick, T., Schulz, E., Hummert, S., Sattler, C., Schmauder, R., and Benndorf, K., (2022):
Subunit promotion energies for channel opening in heterotetrameric olfactory CNG channels
PLoS Comput. Biol. (2022) 18 (8): e1010376

Schirmeyer, J., Hummert, S., Eick, T., Schulz, E., Schwabe, T., Ehrlich, G., Kukaj, T., Wiegand, M., Sattler, C., Schmauder, R., Zimmer, T., Kosmalla, N., Münch, J., Bonus, M., Gohlke, H., and Benndorf, K. (2021):
Thermodynamic profile of mutual subunit control in a heteromeric receptor
PNAS (2021): Proc. Natl. Acad. Sci. 118 (30): e2100469118

Sattler, C., Eick, T., Hummert, S., Schulz, E., Schmauder, R., Schweinitz, A., Unzeitig, C., Schwede, F., and Benndorf, K. (2020):
Unravelling the intricate cooperativity of subunit gating in P2X2 ion channels
Sci. Rep. 10, 21751

Hummert, S.; Thon, S.; Eick, T.; Schmauder, R.; Schulz, E.; Benndorf, K.:
Activation gating in HCN2 channels
PLoS ComputBiol 14(3):e1006045.
doi.org/10.1371/journal.pcbi.1006045
Published: March 22, 2018

Wongsamitkul, N.; Nache, V.; Eick, T.; Hummert, S.; Schulz, E.; Schmauder, R.; Schirmeyer, J.; Zimmer, T.; Benndorf, K.:
Quantifying the cooperative subunit action in a multimeric membrane receptor,
Sci Rep. 2016, Feb 9; 6:20974. doi: 10.1038/srep20974.

Thon, S.; Schulz, E.; Kusch, J.; Benndorf, K.:
Conformational Flip of Nonactivated HCN2 Channel Subunits Evoked by Cyclic Nucleotides.
Biophys J. 109(11):2268-76
2015

Nache, V.; Eick, T.; Schulz, E.; Schmauder, R.; Benndorf, K.:
Hysteresis of ligand binding in CNGA2 ion channels,
Nature Communications 4, Article number: 2864, doi:10.1038/ncomms3866
2013

Benndorf, K.; Kusch, J.; Schulz, E.:
Probability Fluxes and Transition Paths in a Markovian Model Describing Complex Subunit Cooperativity in HCN2 Channels.
PLoS Comput. Biol. 8(10): e1002721. doi:10.1371/journal.pcbi.1002721
2012

Benndorf K, Thon S, Schulz E.:
Unraveling subunit cooperativity in homotetrameric
HCN2 channels. Biophys J. 2012 Nov 7;103(9):1860-9. doi: 10.1016/j.bpj.2012.09.024.

Kusch, J.; Thon, S.; Schulz, E.; Biskup, C.; Nache, V.; Zimmer, T.; Seifert, R.; Schwede, F.; and Benndorf, K.:
How subunits cooperate in homotetrameric HCN2 pacemaker channels
Nature Chem. Biol. 2012 . 8(2):162-169. doi: 10.1038/nchembio.747.

Kusch, J.; Biskup, C.; Thon, S.; Schulz, E.; Nache, V.; Zimmer, T.; Schwede, F; and Benndorf, K.:
Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels,
Neuron 67 (1) (2010a): 75-85.

Schulz, E.; Biskup, C.; Benndorf, K.; Kusch, J.:
Globale Fits von Ionenkanal-Daten an Markov-Modelle,
in Tagungsband Symposium Vigilanz Schmalkalden 2010, ISBN 978-3-00-031422-3, S 57-59

Kusch, J.; Zimmer, T.; Holschuh, J.; Biskup, C.; Schulz, E.; Nache, V.; and Benndorf, K.:
Role of the S4-S5 linker in CNG channel activation.
Biophys J. 99 (2010b): 2488-2496

Christoph Biskup, Jana Kusch, Eckhard Schulz, Birgit Hoffmann, Vasilica Nache, Frank Schwede, Frank Lehmann, Klaus Benndorf:
Adding new dimensions to fluorescence microscopy,
Proceedings of SPIE (2009), Vol. 7183 718308-1 -12, DOI: 10.1117/12.809706

Nache, V.; Kusch, J.; Biskup, C.; Schulz, E.; Zimmer, T.; Hagen, V.; and Benndorf, K.:
Thermodynamics of Activation Gating in Olfactory-Type Cyclic Nucleotide-Gated (CNGA2) Channels.
Biophys. J. 95 (6) (2008): 2750-2758; (Article)

Biskup, C., Kusch, C., Schulz, E., Nache, V., Schwede, F., Lehmann, F., Hagen, V. and Benndorf, K.:
Relating ligand binding to activation gating in CNGA2 channels,
Nature 446 (2007), 440-443 (letter)

Dräger, G.; Schulz, E.; Czolbe W.:
Polarized VBXES and XANES of GaSxSe1−x (x = 0, 0.6, 1),
physica status solidi (b) 169 (1992) 2, 405–415
Article first published online: 19 FEB 2006
onlinelibrary.wiley.com/doi/10.1002/pssb.2221690214/abstract
DOI: 10.1002/pssb.2221690214, Copyright © 1992 WILEY-VCH Verlag GmbH & Co. KGaA

Schulz, E.; Dräger, G.; Czolbe, W.; Brümmer, O.:
X-Ray Spectroscopic Investigations of Titanium Oxides and Basic Materials for Ferroelectric Ceramics,
physica status solidi (a) 111 (1989), 361–365,
Article first published online: 16 FEB 2006
onlinelibrary.wiley.com/doi/10.1002/pssa.2211110138/abstract
DOI: 10.1002/pssa.2211110138, Copyright © 1989 WILEY-VCH Verlag GmbH & Co. KGaA

Dräger, G.; Czolbe, W.; Schulz, E.; Simunek, A.; Drahokoupil, J.; Kucherenko, Yu. N.; Nemoshkalenko, V. V.:
Valence Band Investigations of GaS by Means of Polarized X-Ray Emission Spectra,
physica status solidi (b) 131 (1985) 1, 193-102
Article first published online: 15 FEB 2006
onlinelibrary.wiley.com/doi/10.1002/pssb.2221310119/abstract
DOI: 10.1002/pssb.2221310119, Copyright © 1985 WILEY-VCH Verlag GmbH & Co. KGaA

Nache, V.; Schulz, E.; Zimmer, T.; Kusch, J.; Koopmann, R.; Hagen, V. and Benndorf, K.:
Activation of olfactory-type cyclic nucleotide-gated (CNGA2) channels is highly cooperative
J. Physiol. 569 (2005), 91-102.

Schulz, E.; Nache, V.; Koopmann, R. and Benndorf, K.:
Beschreibung der Schaltkinetiken von CNG-Ionenkanälen durch Markov-Modelle,
fhs-prints, Sonderheft, Tagungsband „Tag der Forschung 2004“ , 109-120

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