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BioMatPur

Development of Cause-and-Effect Models for Describing the Biocompatibility and Material Properties of Thermoplastic Polyurethanes, Considering Processing Factors

Subject of research

  • Development of a Cause-and-Effect Model for Identifying the Material Properties of TPU Relevant to Catheter Products in Correlation with Processing Parameters, Determination of Property-Critical Process Parameters
  • Development of a Cause-and-Effect Model for Biocompatibility in Relation to Processing Parameters for TPU in Medical Catheter Systems, Determination of Biocompatibility-Critical Process Parameters
  • Verification of the Developed Model Approaches for Existing Catheter Systems and Transfer to Novel Isocyanate-Free Polyurethane Systems

Results

  • Model-Based Prediction of Material Properties and Biocompatibility of TPU
  • Optimization of Biocompatibility and Cytotoxicity Testing
  • Transfer of Models to Novel, Isocyanate-Free Polyurethanes
  • Identification of Process-Critical Parameters

Involved organisations and persons

Schmalkalden University of Applied Sciences
Prof. Dr.-Ing. Stefan Roth
Projektleiter: Prof. Dr.-Ing. Thomas Seul

Osnabrück University of Applied Sciences
Prof. Dr. Markus Susoff
Prof. Dr. Svea Petersen

B. Braun Melsungen AG
Stefan Mörl

Third-Party Funders

Bundesministerium für Bildung und Forschung

Additional information